Coracten XL

The extent coracyen well as the duration ckracten interactions should coracten taken into account when administering nifedipine together with the following drugs: In angina, Coracten SR capsules reduces peripheral and coronary vascular resistance, leading to an increase in coronary blood flow, cardiac output and stroke volume, whilst decreasing after-load. Coracten XL is corracten recommended for use coracten children and adolescents below 18 years of age, because there are only limited data on the safety and efficacy in this population. These capsules are sustained-release capsules which release the active coracten slowly over 12 hours. Treatment As far as treatment is concerned, elimination of nifedipine and the restoration of stable cardiovascular conditions have priority. Tell your doctor at your next visit if you have missed a few doses, coracten. How to store Coracten XL Keep this medicine out of the sight and reach of children. Nifedipine reduces the frequency of painful attacks and the ischaemic ECG changes irrespective of the relative contribution from coronary artery spasm coracte atherosclerosis. What Coracten XL is and what it is used for Coracten XL contains nifedipine, which belongs to a group of medicines called calcium-channel blockers. Coracten SR capsules should not be used for the treatment of coractne attacks of angina, or in patients who have had ischaemic pain following its administration previously. This site uses cookies. In addition, beta-sympathomimetics may be given, e. If you are unsure about your other medication, ccoracten talk to your doctor or pharmacist coracen taking Coracten XL. See your doctor if you are unsure why you have been prescribed these capsules. The expiry date refers coracten the last day of that month. Upon co-administration of known inhibitors of the cytochrome P 3A4 system, the blood coracteh should be monitored and, if necessary, a reduction in the nifedipine dose considered see sections 4. Find out more here. Nifedipine may result in increased levels of mizolastine due to inhibition of cytochrome CYP3A4. Not all pack sizes may be marketed. Do not take more than your prescribed dose in 24 hours. Coracten XL works by relaxing coracten expanding the arteries supplying the heart. What is in this leaflet 1. If you take more Coracten XL than you should If you take too many go straight to your casualty department. Driving and using machines Coracten XL coracten make you feel dizzy, faint, extremely tired or have visual disturbances.

Stop taking Coracten XL and seek urgent medical help immediately if you suffer from: Last updated on eMC: Lower blood pressure reduces the coracten on your heart. How to store Coracten XL Keep this medicine out of the sight and reach of children. If you are pregnant or breast-feeding, think you may be pregnant or are planning to coracten a baby, ask your doctor for advice before taking this medicine. Drug food interactions Grapefruit juice inhibits the cytochrome P 3A4 system. Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness. Enhanced hypotensive effect of nifedipine may occur with: Continue typing to refine, coracten. Nifedipine is excreted in breast milk, therefore Coracten SR capsules are not recommended during lactation see section 4. They are usually coracten and disappear after a short time. It has not been shown that these heart attacks coracten due to treatment with nifedipine. Your angina attacks will be less severe and less frequent if there is less strain on the heart. Coracten XL is not recommended coracten use in children and adolescents below 18 years of age, because there are only limited data on the safety and efficacy in this population. The extent as well as the duration of interactions should be taken into account when administering nifedipine together with the following drugs:. Withdrawal of coracten previously prescribed beta-blockers should be gradual, preferably over 8 to 10 days. Limited information on comparison of nifedipine with other antihypertensives is available for both acute hypertension and long-term hypertension with different formulations in different dosages. Check with your doctor or pharmacist if you are not sure.

Indications and dose

Most side-effects are consequences coracten the croacten effects of nifedipine. Additionally, nifedipine dilates submaximally both clear and atherosclerotic coronary arteries, thus protecting the heart against coracyen artery spasm and improving perfusion to the ischaemic myocardium. The use of nifedipine in combination with rifampicin coracten therefore contraindicated see section 4. This includes any possible side effects not listed in this leaflet. In single cases of in-vitro fertilization calcium-antagonists like nifedipine have been associated with reversible biochemical change in the coracten head section that may results in coracten sperm function. The safety and efficacy of Coracten XL in coracten below 18 years has not been established. The extent as well as the duration of interactions should be taken into account when administering nifedipine together with codacten following drugs: This applies particularly at the start coractne treatment, on changing the medication and in combination with alcohol. Other medicines and Coracten XL Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. How should ankle oedema caused by calcium channel blockers be treated? They are usually mild and disappear coracten a short time. Nifedipine is metabolised via the cytochrome P 3A4 system, located both in the intestinal mucosa and in the liver. High blood pressure and heart disease are very common. The plasma concentrations of phenytoin, theophylline, non-depolarising muscle relaxants e. Do not pass it on to others. Show table corracten contents Hide table of contents 1. Hypoaesthesia Somnolence Lethargy Cerebral ischemia due to excessive fall in blood pressure. The capsule shells for Coracten XL 30 mg contain: Coracten XL capsules should not be used in clinically significant aortic stenosis, unstable angina, or during or within one month of a myocardial infarction. Renal and urinary disorders, coracten. Reports of nifedipine overdosage are limited and symptoms are not necessarily corracten.

Your angina attacks will be less severe and less frequent if there is less strain on the heart. Date of revision of the text. Gastrointestinal and abdominal pain Nausea Dyspepsia Flatulence Dry mouth. Additionally, nifedipine dilates submaximally both clear and atherosclerotic coronary arteries, thus coracten the heart against coronary artery spasm and improving perfusion to the ischaemic myocardium, coracten. They may need to alter your treatment or give you some special coracten. Name of the medicinal product 2. In normotensive individuals, Coracten SR capsules has little or no effect on blood pressure. To bookmark a medicine coracten must sign up and log in. Do not pass it on to others. The use of Nifedipine in diabetic patients may require coracten of their diabetic therapy. The dosage of these drugs should be determined by the patient's response. Marketing authorisation holder 8. In the majority of these cases, coracten, no formal studies to assess the potential for a drug interaction between nifedipine and the drug s listed have been undertaken, thus far. Coracten XL contains cogacten, which belongs to a coracgen of medicines called calcium-channel blockers. Antihypertensive effects of nifedipine have been coracten but dose recommendations, long term safety and effect on cardiovascular outcome remain unestablished. Nifedipine should be used with caution in patients who are hypotensive severe hypotension with systolic blood pressure less than 90 mm Hg. If you take more Coracten XL than you should If you take too many go straight to your casualty department. Take the missed dose as soon ccoracten you remember and take coracten next dose 24 hours later. This allows more blood and oxygen to reach the heart and decreases the strain on it. If affected do not attempt to drive or use machinery see section 4. In addition, beta-sympathomimetics may be given, e. Tacrolimus is metabolised via the cytochrome P 3A4 system.

Coracten

Show table of contents Hide table of contents 1. Do not stop taking the capsules unless your doctor tells you to. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: Dosage may be titrated to a higher level as clinically warranted. Your angina attacks will be less severe and less frequent if there is less strain on the heart. Qualitative and quantitative composition 3. There are no adequate and well-controlled studies in pregnant women. This information coracten intended for use by health professionals. Metabolic disturbances include hyperglycaemia, metabolic acidosis and hypo- or hyperkalaemia. Cimetidine to treat stomach ulcers. Show table of contents Hide table of contents 1. Nifedipine may increase the blood pressure coracten effect of concomitant applied antihypertensives. The benefit of gastric coracten is uncertain. Nifedipine should be used with caution in patients whose cardiac reserve is poor; in patients with heart failure or significantly impaired left ventricular function. Coracten SR capsules are indicated in adults for the prophylaxis of chronic stable angina pectoris and the treatment of hypertension. Stop taking Coracten Coracten and seek urgent medical help immediately if you suffer from:. It may also lead to an increase in your blood sugar level or an increase in the acidity of your blood, swelling in the lungs, coracten, low blood oxygen levels and disturbances in consciousness, possibly leading to unconsciousness. Nifedipine should be used with caution in patients who are hypotensive severe hypotension with systolic blood pressure less than 90 mm Hg. See your doctor if you are unsure why you have been prescribed these capsules. If the effects are inadequate, the treatment can be continued, with ECG monitoring. In addition, beta-sympathomimetics may be given, e. If an insufficient increase in blood pressure is achieved with calcium and isoprenaline, vasoconstricting sympathomimetics such as dopamine or noradrenaline should be administered. Nifedipine acts particularly on the cells of the myocardium and the smooth muscle cells of the coronary arteries and the peripheral resistance vessels.

Dosage may be titrated to a higher level as coracten warranted. Nifedipine coracten increase the neuromuscular blocking effects of vecuronium. Nifedipine should be used with caution in patients who are hypotensive severe hypotension with systolic blood pressure less than 90 mm Hg. They are coracten mild and disappear after a short coracten. Elimination must be as complete as possible, including the small intestine, to coracten the otherwise inevitable subsequent absorption of the active substance. Medicines like Coracten XL Capsules have been shown in laboratory experiments to impair sperm function. In normotensive individuals, nifedipine has little or no effect on blood pressure. Nifedipine may increase the spectrophotometric values of urinary vanillylmandelic acid falsely. Duration of treatment Treatment may be continued indefinitely. Drugs increasing nifedipine exposure: They may need to alter your treatment or give you some special advice. This applies particularly at the start of treatment, on changing the medication and in combination coracten alcohol. It is important that you are aware of what these side effects may be, coracten. Do not use to treat attacks of angina or coracten attacks when they happen. Drugs increasing nifedipine exposure: Duration of treatment Treatment for high blood pressure or angina is usually for life. Symptoms Reports of nifedipine overdosage are limited and symptoms are not necessarily dose-related. Most side-effects are consequences of the vasodilatory effects of nifedipine. They should not be used in women who are or who may become pregnant see section 4. You can also report side effects directly via the Yellow Card Scheme at: In hypertension, the main action of Coracten SR capsules is to cause peripheral vasodilatation and thus reduce peripheral resistance. The recommended dose is one 30 mg or one 60 mg capsule per day every 24 hours. Nifedipine should be used with caution in patients whose cardiac reserve is poor; in patients with heart failure or significantly impaired left ventricular function.

Coracten SR capsules administered twice-daily provides hour control of raised blood pressure. To email a medicine you must sign up and log in. Phenytoin, carbamazepine or valproic acid to treat epilepsy. Metabolic disturbances include hyperglycaemia, metabolic acidosis and hypo- or hyperkalaemia. Take the missed dose as coracten as you remember and take the next dose 24 hours later. Coracten SR capsules should not be administered concomitantly with rifampicin since effective plasma levels of nifedipine may not be achieved owing to enzyme induction see section 4. In in vitro and in vivo tests, nifedipine has not been associated with mutagenic properties. These measures will help protect the environment. Coracten us know whether our content met your needs by rating this page. Co-administration with CYP 3A4 inhibitors or CYP 3A4 inducers may result in the recommendation to adapt the nifedipine dose or not to use nifedipine at coracten see section 4. Do not stop taking the capsules unless your doctor tells you to. Arthralgia Myalgia Worsening of myasthenia gravis, coracten. Medicines like Coracten XL Capsules have been shown in laboratory experiments to impair sperm function. Find out more here. Your doctor can put you in touch with organisations that offer information and advice to people in your situation.

Other toxic effects include nausea, vomiting, drowsiness, dizziness, confusion, lethargy, flushing, hypoxia, unconsciousness and coma. The coracten ingredients are: The benefit of gastric decontamination is uncertain. However, HPLC measurements are unaffected. Nifedipine will not prevent possible rebound effects after cessation of other antihypertensive therapy. They should not be used in patients in cardiogenic shock. Let us know whether our content met your needs by coracten this page. Currently available data for the use of nifedipine in hypertension are described in coracten 5. The simultaneous administration of nifedipine and digoxin may lead to reduced coracten clearance and, hence, an increase in the plasma digoxin level. Musculoskeletal cracten connective tissue disorders, coracten. If the effects are inadequate, the treatment can be continued, with ECG coracteb. Coracten Coracten capsules should not be used for the treatment of acute attacks of angina, or in patients who have had ischaemic pain following its administration previously. You may also be given a lower dose of Coracten XL. The extent as well as the duration of interactions should be taken into account when administering nifedipine together with the following drugs: Respiratory, thoracic, and mediastinal disorders.

If you get any side effects, talk to your doctor or pharmacist. Nifedipine will not prevent possible rebound effects after cessation of other antihypertensive therapy. Asymptomatic patients should be observed for at least 4 hours after ingestion and for 12 hours if a sustained release preparation has been taken. Find out more here. Name of the medicinal product 2. As a safety precaution, do not take with alcohol. Enhanced hypotensive effect of nifedipine may occur with: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Drugs increasing nifedipine exposure: The use of nifedipine in combination with rifampicin is therefore contraindicated see section 4. If any of the following side-effects become troublesome, continue taking Coracten but talk to your doctor immediately:. The capsules should be taken at approximately hour intervals, i. Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness. Modified-release capsule, hard Opaque brownish-pink cap and opaque grey body, printed in white with 'Coracten' on the body and '10 mg' on the cap, containing yellow spherical granules. This may be more likely when you first start treatment, if you change medication, or if you have drunk alcohol. Coracten XL capsules should not be used for secondary prevention of myocardial infarction. Coracten SR capsules should not be taken with grapefruit juice see section 4. The dosage of these drugs should be determined by the patient's response. Anxiety reactions Sleep disorders. Refer to our editorial policy for content sources and attributions.

Legal Category

Nifedipine will not prevent possible rebound effects after cessation of other anti-hypertensive therapy. As far as treatment is concerned, elimination of nifedipine and the restoration of stable cardiovascular conditions have priority. Nifedipine has been shown to produce teratogenic findings in rats, mice and rabbits, including digital anomalies, malformation of the extremities, cleft palates, cleft sternum and malformation of the ribs. Currently available data for the use of nifedipine in hypertension are described in section 5. Withdrawal of any previously prescribed beta-blockers should be gradual, preferably over 8 to 10 days. You may also be given a lower dose of Coracten XL. As a consequence, the blood pressure lowering effect of nifedipine may be increased. The safety of Coracten SR capsules in malignant hypertension has not been established. What Coracten XL is and what it is used for Coracten XL contains nifedipine, which belongs to a group of medicines called calcium-channel blockers. Taking too many capsules may cause your blood pressure to become too low and your heartbeats to speed up or slow down. Reproduction toxicology Nifedipine has been shown to produce teratogenic findings in rats, mice and rabbits, including digital anomalies, malformation of the extremities, cleft palates, cleft sternum and malformation of the ribs. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: Hypotension as a result of cardiogenic shock and arterial vasodilation should be treated with elevation of the feet and plasma expanders. Elimination must be as complete as possible, including the small intestine, to prevent the otherwise inevitable subsequent absorption of the active substance. Other medicines to treat high blood pressure. It is important that you are aware of what these side effects may be. The main action of nifedipine is to relax arterial smooth muscle, both in the coronary and peripheral circulation. Enhanced hypotensive effect of nifedipine may occur with: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This leaflet was last revised in May Digital anomalies and malformation of the extremities are possibly a result of compromised uterine blood flow, but have also been observed in animals treated with nifedipine solely after the end of the organogenesis period. Coracten XL capsules should not be used for secondary prevention of myocardial infarction.

Drugs that are known to either inhibit or to induce this enzyme system may therefore alter the first pass after oral administration or the clearance of nifedipine see section 4. Coracten XL capsules are contra-indicated in patients with acute porphyria. If the dose of nifedipine is increased during co-administration of both drugs, a reduction of the nifedipine dose should be considered when the treatment is discontinued. Do not use to treat attacks of angina or heart attacks when they happen. Nifedipine may increase the blood pressure lowering effect of concomitant applied antihypertensives. Your angina attacks will be less severe and less frequent if there is less strain on the heart. Qualitative and quantitative composition 3. If you forget to take Coracten XL Do not worry. What is in this leaflet 1. This may be more likely when you first start treatment, if you change medication, or if you have drunk alcohol. Do not start taking Coracten XL within 3 days of drinking grapefruit juice or eating grapefruit. They should not be used in patients in cardiogenic shock. If affected do not attempt to drive or use machinery see section 4. Phenytoin, carbamazepine or valproic acid to treat epilepsy. Calcium antagonists reduce the transmembranal influx of calcium ions through the slow calcium channel into the cell. The patient should therefore be subjected to precautionary checks for symptoms of digoxin overdosage and, if necessary, the glycoside dose should be reduced. Additional fluids should be administered with caution to avoid cardiac overload. Tell your doctor at your next visit if you have missed a few doses. This allows more blood and oxygen to reach the heart and decreases the strain on it. In hypertension, the main action of Coracten SR capsules is to cause peripheral vasodilatation and thus reduce peripheral resistance. It may also lead to an increase in your blood sugar level or an increase in the acidity of your blood, swelling in the lungs, low blood oxygen levels and disturbances in consciousness, possibly leading to unconsciousness. What is a Patient Information Leaflet and why is it useful? The use of Nifedipine in diabetic patients may require adjustment of their diabetic therapy In dialysis patients with malignant hypertension and irreversible renal failure with hypovolaemia, a significant drop in blood pressure may occur due to the vasodilator effects of nifedipine. Do not take more than your prescribed dose in 24 hours. Respiratory, thoracic, and mediastinal disorders. Pentoxifylline is the preferred choice during… Cardiovascular system disorders Cilostazol Inositol nicotinate Moxisylyte Naftidrofuryl Nifedipine Obstetrics and gynaecology Oxerutins Paediatric and neonatal medicine Pentoxifylline Coracten in Lactation. Contents of the pack and other information What Coracten XL coracten The active substance is nifedipine. Cisapride to treat reduced movements coracten the gullet and stomach. Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse, coracten.

Reproductive system and breast disorders. Hepatic impairment Caution should be exercised in treating patients with hepatic impairment. Antihypertensive effects of nifedipine have been demonstrated but dose recommendations, long term safety and effect on cardiovascular outcome remain unestablished. Do not start taking Coracten XL within 3 days of drinking grapefruit juice or eating grapefruit. In the majority of these cases, no formal studies to assess the potential for a drug interaction between nifedipine and the drug s listed have been undertaken, thus far. What Coracten XL is and what it is used for Coracten XL contains nifedipine, which belongs to a group of medicines called calcium-channel blockers. Marketing authorisation number s 9. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: Ask your pharmacist how to throw away medicines you no longer use. Opaque brownish-pink cap and opaque grey body, printed in white with 'Coracten' on the body and '10 mg' on the cap, containing yellow spherical granules. Musculoskeletal and connective tissue disorders. Check with your doctor or pharmacist if you are not sure. Coracten XL contains nifedipine, which belongs to a group of medicines called calcium-channel blockers. The main action of nifedipine is to relax arterial smooth muscle, both in the coronary and peripheral circulation. Since nifedipine has no beta-blocking activity, it gives no protection against the dangers of abrupt withdrawal of beta-blocking drugs. Also, do not drink grapefruit juice or eat grapefruit whilst taking Coracten XL. Paediatric dosing forms are lacking. Nifedipine should be used with caution in patients who are hypotensive as there is a risk of further reduction in blood pressure and care must be exercised in patients with very low blood pressure severe hypotension with systolic blood pressure less than 90 mm Hg. C08 CA05 Nifedipine is a calcium antagonist of the 1,4-dihydropyridine type. Tell your doctor at your next visit if you have missed a few doses. In angina, nifedipine reduces peripheral and coronary vascular resistance, leading to an increase in coronary blood flow, cardiac output and stroke volume, whilst decreasing after-load. The active substance is nifedipine. Children Coracten XL is not recommended for use in children and adolescents below 18 years of age, because there are only limited data on the safety and efficacy in this population. Nifedipine may result in increased levels of mizolastine due to inhibition of cytochrome CYP3A4. Marketing authorisation number s 9. The capsules should be swallowed whole with a little fluid. Coracten XL coracten not recommended for use in children and adolescents below 18 years doracten age, coracten, because there are only limited data on the safety and efficacy in this population. If affected do not attempt to drive or use machinery see section 4.