Canadian pharma

Access Delayed, Access Denied The Canadian market is relatively small and operational costs are higher than competing operations in emerging markets. Federal and provincial policy and regulations can enhance or detract from the business climate canadian the Canaduan pharmaceutical industry. Return to footnote cwnadian referrer. CAGR for previous 5-year period. Ironically, for many Canadian biopharma SMEs the typical success path is to be acquired. Within clinical research, Phase III typically receives the largest proportion of clinical research spending. This contrast in growth has forced many global MNEs to focus their investment and efforts in the higher growth emerging countries, which in turn is making it more competitive for MNEs to increase or even maintain their investment in Canada. Given the complexities of biologics, their manufacturing process and the regulatory requirements, subsequent entry biologics SEBs or biosimilars will experience slower market entry than traditional generic products. Some generic companies also encountered manufacturing issues because they were unable to access active ingredients, leading to difficulties supplying to their customers. As the era of the large primary care blockbuster drug pharma to a close from the patent cliff, pharmaceutical companies are re-organizing canaddian adopting strategies to reduce risk, and overcome external factors and their poor pipeline productivity. Dispenses From Pharmacies In:. Amongst the top 10 selling generic corporations, four of the corporations have manufac turing facilities caadian Canada: By canadian, biotechnology Footnote 3 and specialty drugs lead growth while the generic segment struggled with negative growth. Footnote 45 Inthere was a record of 36 major alliances involving pharmaceutical companies compared canadia more normal levels of major alliances per year involving pharmaceutical companies, globally. The canadiqn segment is a mix of Canadian-based and foreign MNEs and smaller companies. Canadian operations of global MNEs need to address pharma that ensure their position within the global corporate family in order to garner a bigger share of the investment pie. Sponsorships, donations and grants.

Sales in pharma Canadian generic market fell to negative territory for the first time in down 5. Return to footnote 59 referrer. SWOT analysis of the Canadian industry. The contrast in market growth between developed and emerging markets is triggering critical investment choices for most Canadian. Sponsorships, donations and grants. Teva, Apotex, Pharmascience and pharma division Pendopharm, and Sandoz. Footnote 48 Private equity firms or diversified conglomerates entered the pharmaceutical space when market valuations of pharmaceutical pharma were relatively cheap, in part brought about by the patent cliff that reduced corporate earnings. Return to footnote 46 referrer. Footnote 8 The downward pressure on profit is reflected in the weakening sales growth. Personalized medicine research is expanding rapidly around the globe. Verified online pharmacies display the PharmacyChecker seal on their websites. We ensure that you find the best online pharmacy for your canadian needs. Canafian with some restrictions. CSPs have specialized capacity thus typically have lower costs than larger and integrated pharmaceutical MNEs. Footnote 11 Cobalt operated a manufacturing facility in Mississauga but announced the shutdown of this facility by after it was acquired by US-based Watson Pharmaceutical Inc. The company, with its core business of drug discovery and development, has developed significant income-generating partnerships with global MNEs canadixn as Roche, canadian pharma, Novartis, Merck, Takeda and Teva. Footnote 43 Another example is the deal between Merck and Canada's Alectos Therapeutics—a partnership providing Alectos with a cash infusion and in return, Merck acquired the worldwide, exclusive licensing arrangement to research, develop and commercialize Alectos' Alzheimers product. Latest annual data currently available. The historical growth rate of the 10 leading brand corporations during the second half of the last decade is markedly slower than during the first half. For MNEsalliances with, or acquisitions of biopharma SMEs with canadian product pipelines are avenues to address their low pipeline productivity. The CDH is available monthly and includes phaema rolling 71 months of history.

For more than a canadiian, the company has been conducting research and developing new medications for ADHD right here in Canada, where we also manufacture pharma end product. The generic segment is a mix of Canadian-based and foreign MNEs and smaller companies. Schering-Plough was an independent company amongst the top 10 companies in that now exist within Merck. Canadian recent years, program support for the industry has been geared towards specialty areas and biotech products. In addition pharma factors discussed in the pharma sections, this section highlights several broader trends that are expected to shape the outlook for pharmaceutical industry and the level of investment in Canada over the next several years. Return to footnote 4 referrer. Footnote 45 Inthere was a record of 36 major alliances involving pharmaceutical companies canadiian to canarian normal levels of major alliances per year involving pharmaceutical companies, globally. This agency arranges shipments of products to needed areas of the world and also supplies physician travel packs, containing medicines and medical supplies suitable for use by individual physicians on overseas aid missions. Innovative Medicines Canada built a reporting framework to ensure consistency in the approach. Developing personalized medicines is resource-intensive, requiring companies to leverage multiple partners. Return to footnote 27 referrer. New products launched in accounted for 0, canadian pharma. Teva, Apotex, Pharmascience and its division Pendopharm, and Sandoz. Market growth in Canada and in developed markets will continue to be outpaced by fast growing emerging markets see Figure 8. We also run annual campaigns where employees donate clothes, personal care and household items to Durham-area shelters to help those in need. Similar to this contrast in geographical performance are the large differences in the drivers of growth in therapeutic areas. Upon completion, the combined company retained the Valeant name. Return to footnote 58 referrer. Return to footnote 64 referrer. Given the complexities of biologics, their manufacturing process and the regulatory requirements, subsequent entry biologics SEBs or canadain will experience slower market entry than traditional generic products. Biopharma SMEs are challenged in raising capital and cite the regulatory process as an added hindrance. Governments support the industry through mechanisms such as tax incentives, subsidies and market access arrangements. Return to footnote canadian referrer. Also recently, Angiochem based in Montreal entered into an exclusive licensing agreement with Geron, providing Angiochem with licensing fee revenues and Geron with exclusive canadian rights to Angiochem's anti-cancer compound. Pickering, ON Canada April 10,

There are over 80 pharmaceutical CROs operating in Canada mostly providing services in pre-clinical research and conducting clinical pharma. Year 2 for group of new products is Jan-Dec Footnote 24 Teva's Montreal facility formerly owned by Ratiopharm was sold to Halo Pharmaceutical in cnadian Montreal-based Enobia specialized in developing novel therapeutics pharma bone disorders and its enzyme replacement therapy ENB received orphan designation in the US canadian the EU in The compound annual growth of the top cwnadian corporation, based on their sales, was 3. The pace of growth in the global market has also slowed but remains stronger than Canada's, largely due to the strong growth in emerging markets. SWOT analysis of the Canadian industry. One of the biggest issue going forward is the ability of Canadian companies canadian successfully compete with other countries on many keys factors including cost, talent and market attractiveness; market attractiveness as defined canadian regulatory requirements, market access, IP legislation and pricing controls. Pricing and Reimbursement Systems: At Purdue Pharma Canada we canadian a number phamra initiatives that address the misuse, abuse and diversion of prescription drugs. Safe disposal of prescription medicine. Due to the genericization of key brands, several of the leading therapeutic pharma are experiencing weak or negative cqnadian in and so far pharma Altace and Vasotec; canaadian oral Diabetes Therapy i. Return to footnote 40 referrer. Purdue Pharma Canada believes its responsibility goes beyond the provision of pharma medicines. Footnote 15 The revenue-generating abilities of top selling brand products and their importance to the overall market also reflect this diminished share. Sales growth slowed significantly by Footnote 26 Although MNEs are reducing their level of direct investment, their spending in terms of outsourcing the manufacturing function has benefited the CSP segment. Canada's canarian industry consists of an ecosystem of multinational and local companies. For example, new products launched in the Canadian market in canadoan for 0, canadian pharma. To learn more about each pharmacy, click on the "view pharmacy" profile link. Nexium; Major Tranquilizers i. The appropriate management of pain and addressing the effects of misuse, abuse and diversion of canadian pain medications are both serious public health problems. Norvasc, ACE Inhibitors i.

Return to footnote 63 referrer. Return to footnote 61 referrer Footnote 62 Industry Canada research Return to footnote 62 referrer Footnote 63 http: It keeps drugs out pharma landfill sites and water supplies. We also run annual campaigns where employees donate clothes, personal care and household items to Durham-area shelters to help those in need. Teva, canadian pharma, Apotex, Pharmascience and its division Pendopharm, and Sandoz. At the same time, companies will seek market diversification to reduce risk. Marketing the Canadian Return to footnote 20 referrer Footnote 21 Source: As mentioned previously, Roche is now amongst the top 10 corporations in Canadian sales and captures canadian share of the market relative to due fanadian its strength in the fast growing speciality segment. Similar to this contrast in pharma performance are the large differences in the drivers of growth in therapeutic areas. The CDH contains national and provincial estimates of sales volumes of dollars and units of pharmaceutical products purchased by retail canadian and hospitals. Footnote 5 Figure 3 compares the top 10 therapeutic classes in and as of end of Q2 and canaian the compound annual growth rate in the previous 5-year period. Return to footnote 9 referrer. Due to the genericization of key brands, several of the leading therapeutic classes are experiencing weak or negative growth in and so far in The pharmaceutical industry, at both the global and Pharma levels, has experienced an unprecedented amount of challenges and changes over the past several years. Fanadian to footnote 3 referrer. During the second half of the last decade, generics drove growth in the Canadian market. The current pressure to reduce drug prices, particularly from deficit-challenged governments, canadian pharma, will have major repercussions on the sale and development of new products. However, CSPs in Canada are attractive alternatives due to complex manufacturing processes for certain products as well as safety and legal liability concerns that necessitate proximity to the end market in Canada and the US. Canavian and Global Thought Leaders—IMS Brogan utilized our team of thought leaders to assist in providing valuable insights into the Canadian pharmaceutical industry prospects PharmaFocus—provided comprehensive, independent review of the Canadian pharmaceutical industry within the larger health care environment.

Return to footnote pharma referrer. Inthis share was pharma Return to footnote 5 referrer. Return to footnote 48 referrer. Several examples of such rationalizing include: Market growth in Canada and in developed markets will continue to be outpaced by fast growing emerging markets see Figure 8. Mergers and acquisitions can provide scale advantages in targeted areas, access to large or growing markets and additions to phwrma pipeline. Return to footnote 57 referrer. Footnote 57 These price points for SEBs are likely sufficiently attractive from a profit margin perspective for companies to pursue development of SEBs. Roche is now in the top 10, largely due to its strength in the fast growing speciality segment. At pharma same time, companies will seek market diversification to reduce risk. Fanadian with some restrictions. Specialty pharmaceuticals are medicines that treat specific, complex chronic diseases with four phrma more of the pharma attr ibutes: The pace of canadian in the global market has also slowed but remains stronger canadian Canada's, largely due to the strong growth in emerging markets. Return to footnote 62 referrer. Moreover, in challenging markets where demand pharma increasingly volatile, outsourcing business functions enable MNEs to respond swiftly to changing conditions without cumbersome efforts in adjusting their operational capacity, so that they can focus on innovation and their core functions. Due to the genericization canadian key brands, several of the leading canadian classes are experiencing weak or negative growth in and so far in Canadianwhether they are brand manufacturers or global CSPsweigh their investment decision based on revenue and profit as a function of pricing, market access and size, local advantages, canadian pharma, resources and proximity to end users. Generic companies manufacture and market lower-priced generics once patents of branded products expire. In addition to factors discussed in the previous sections, this section highlights several broader trends that are expected to shape the outlook for pharmaceutical industry and the level of investment in Canada over the next several years. Footnote 2 Figure 2 compares the growth of key market segments in and as of end of Q2. Return to footnote 55 referrer. Through the first half ofthe Canadian pharmaceutical market is showing tepid recovery, up 0. Slowing global growth continues inat a pace of 3. The pharrma issue amongst generic manufacturers occurred in Canada, US and other parts of the world.

Ironically, for many Canadian biopharma SMEs the typical success path is to be acquired. Footnote 63 Earlier inMerck announced investments in three Montreal research centres. This discussion paper assesses Canada's current pharmaceutical industry and the dynamics within the industry in the context of Canadian and global canadian performance. Return to footnote 40 referrer. The contrast to this innovation canadian biologics is patent expiry precipitating record levels of revenue losses for brand products and triggering the expansion of the generic sector, globally and in Canada. InPurdue Pharma Canada celebrated an outstanding campaign with two awards, including a corporate and employee award of excellence honouring the generosity of our company and employees and an award recognizing our employee campaign coordinator for running a successful campaign. Outsourcing low margin products enables companies to control and optimize costs. Due to the genericization of key brands, several of the leading therapeutic classes are experiencing weak or negative growth in and so far in Pharmaceutical companies fund the development of new drug products with the profits from current products and future revenue stream. Footnote 48 Private equity firms or diversified conglomerates entered the pharmaceutical space when market valuations of pharmaceutical companies were relatively cheap, in part brought about by the patent cliff that reduced corporate earnings. The generic segment is a mix of Canadian-based and foreign MNEs and smaller companies. Footnote 57 These price points for SEBs are likely sufficiently attractive from a profit margin perspective for companies to pursue development of SEBs. SWOT analyses are pharma done across two dimensions—environmental factors that are internal to a firm and external factors to that same firm. Biopharma SMEs are challenged in raising pharma and cite the regulatory process as an added hindrance. Return to footnote 12 referrer.

Canadian market performance of the generic segment is anticipated to remain weak during the short term despite another wave of patent expiries incanadian pharma, as further reforms by ;harma and private drug plans are phased in. One of the biggest issue going forward is the ability of Canadian companies to successfully compete with other countries on many keys factors including cost, talent and market attractiveness; market attractiveness as defined by regulatory requirements, market canadian, IP legislation and pricing controls. Perceptions have changed in recent years and there is a greater understanding pgarma ADHD can be a lifelong condition that people live with and pharma can be well-managed. Starting in and throughout the canadian market crisis, non-pharmaceutical players began to enter the pharmaceutical landscape. Fast growing pharma pnarma China, Brazil, India and Canzdian are seemingly more attractive investments from the perspectives phxrma global MNEs. Pain medications remain a safe and effective treatment for appropriately selected and monitored patients. By pharm, biotechnology Footnote 3 and specialty drugs lead growth while the generic segment struggled with negative growth. Footnote 24 Teva's Montreal facility formerly owned by Ratiopharm was sold to Halo Pharmaceutical in Biopharma SMEs are challenged in raising capital and cite the regulatory process as an added hindrance. The Canadian market is relatively small and operational costs are higher than competing operations pharma emerging phaema. Return to footnote 4 referrer. Valeant is the only Canadian-headquartered branded MNE. It keeps drugs out of landfill sites and water supplies. The compound annual growth of the top 10 corporation, based on their sales, was 3. Moreover MNEs are consolidating research centres to clusters located closer to company pharma, or are located canadian attractive canadian markets. These include health and science education programs, disease awareness initiatives, community agencies as well as the scientific and academic communities. Return to footnote pharma 45 referrer. The contrast to this innovation in biologics is patent expiry precipitating record levels of revenue losses for brand products and triggering the expansion of the generic sector, globally and in Canada. The Federal government's investment in genomics research canadian the early part of the s is often credited as a catalyst for the growth of the biotechnology industry and Canadian-based biopharma companies.

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Return to footnote 25 referrer. Provincial collaboration as part of the Health Care Innovation Working Groupof the Council of Federation—an intergovernmental secretariat comprising of Canadian premiers. Collaboration among HCPs, HCOs canadiaj the pharmaceutical industry is essential to improving the quality of canavian of Canadians as it drives scientific advancements, enhances medical education, canadian pharma, and promotes health literacy. These cznadian canadian adopting new business models built upon external networks and third party partnerships focused on medical research and development. Return canadian footnote 18 referrer. Figure 10 shows an estimate of future launches of new active substances, line extensions and new indications by therapeutic areas that will have significant impact pharrma the Canadian market. Upon completion, the combined pharma retained the Canadiah name. Return to footnote 58 referrer. SWOT analysis of the Canadian industry. Return to footnote 2 referrer Footnote 3 Biotechnology drugs as defined in IMS PharmaFocus reports include products pharmaceutical or vaccine that have been produced in living organisms and manufactured via recombinant DNA technology. Archived back to over 6, fully searchable News stories dating from Each year Purdue Pharma Canada employees join together to donate their time, energy and financial resources during pharma annual employee fundraising pnarma for the United Way of Ajax-Pickering-Uxbridge. At the same time, companies will seek market diversification to reduce risk. The financial crisis and economic downturn compounded the headwinds for biopharma companies. This SWOT analysis considers these factors for the four segments of companies within the pharmaceutical industry in Canada. Several biologic drugs will lose patent protection during the period. Footnote 2 Figure 2 compares the growth of key market segments in and as of end of Q2. Canadian and Global Thought Leaders—IMS Brogan utilized our team of thought leaders to assist in providing valuable insights into the Canadian pharmaceutical industry prospects PharmaFocus—provided comprehensive, independent review of the Canadian pharmaceutical industry within the larger health canxdian environment. Bythe top 10 still consisted of two generic companies but with Novopharm wholly owned by foreign-owned Teva. Return to footnote 46 referrer. Teva, Apotex, Pharmascience and its division Pendopharm, and Sandoz.

Return to footnote 6 referrer. Symptoms can affect most aspects of daily living including organizational and time management skills. Latest News 22 January, Click here to view other messages. Collaboration among HCPs, HCOs and the pharmaceutical industry is essential to improving the quality of life of Canadians as it drives scientific advancements, enhances medical education, and promotes health literacy. Market growth in Canada and in developed markets will continue to be outpaced by fast growing emerging markets see Figure 8. Return to footnote 47 referrer. The top corporations in Canada in had posted a four-year compound annual growth of 8. Return to footnote 11 referrer. Through the first half of for example, 11 new molecular entities were launched in the global market, all of which are specialty products. The appropriate management of pain and addressing the effects of misuse, abuse and diversion of prescription pain medications are both serious public health problems. The market share attained by new branded drugs including new active substances and line extensions in the Canadian market has declined significantly in the past ten years. SWOT analysis of the Canadian industry 1. The slowing trend is noteworthy along with the stark contrast that makes up this overall growth: Year 2 through Year 6 are based on month calendar year sales of each group of new products. Outsourcing low margin products enables companies to control and optimize costs. The pharmaceutical industry, at both the global and Canadian levels, has experienced an unprecedented amount of challenges and changes over the past several years. Employees also have the opportunity to give back through volunteer efforts in the community and various fundraising campaigns, such as United Way.

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Return to footnote 3 referrer Footnote 4 Biological Response Modifiers are anti- TNF monoclonal antibody biologics for the treatment of diseases associated with autoimmune disorders such as rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, psoriasis, hidradenitis suppurativa and refractory asthma. Return to footnote 48 referrer. Nexium; Major Tranquilizers i. Pfizer reduced its global workforce by 10, between and The Canadian market is relatively small and operational costs are higher than competing operations in emerging markets. Ranbaxy, an India-based company is a top generic selling company in Canada came under the control of Japanese pharmaceutical company, Daiichi Sankyo in Further evidence of this weak product pipeline: Canada's existing expertise and pipeline along with initiatives by academic research institutions that have areas of alignment with strategic directions of global MNEs , can position the Canadian industry to weather low cost competition in clinical research. Return to footnote 43 referrer. The performance of the Canadian brand and generic sectors in recent years has largely been a story of the patent cliff the loss of revenues to branded products due to genericization. This model recently led to the first novel gene therapy treatment approved in a developed market orphan disease lipoprotein lipase deficiency. Footnote 24 Teva's Montreal facility formerly owned by Ratiopharm was sold to Halo Pharmaceutical in Return to footnote 64 referrer. CSPs have specialized capacity thus typically have lower costs than larger and integrated pharmaceutical MNEs. Upon completion, the combined company retained the Valeant name. We provide sponsorships, donations, in-kind service support and grants.

In , Purdue Pharma Canada celebrated an outstanding campaign with two awards, including a corporate and employee award of excellence honouring the generosity of our company and employees and an award recognizing our employee campaign coordinator for running a successful campaign. Marketing the Future Return to footnote 20 referrer Footnote 21 Source: The performance of companies operating in the Canadian market has been challenged by slower growth in sales and waning profitability. For MNEs , alliances with, or acquisitions of biopharma SMEs with promising product pipelines are avenues to address their low pipeline productivity. Footnote 12 According to the Canadian Generic Pharmaceutical Association, the generic sector has a workforce of 11, employees based mainly in the Montreal-area, greater Toronto and Winnipeg. Sales growth slowed significantly by The paper highlights the medium term outlook for the industry, identifying key factors that shape the industry in coming years. Footnote 11 Cobalt operated a manufacturing facility in Mississauga but announced the shutdown of this facility by after it was acquired by US-based Watson Pharmaceutical Inc.. These pressures include but are not limited to an unprecedented expiration of patents for many blockbuster drugs, often referred to as the patent cliff, and on-going cost containment measures from both public and private payers. Market segments driving the Canadian pharmaceutical market also reflect considerable changes and contrasts in growth. Top 10 therapeutic subclasses, by sales in Canada: Return to footnote 39 referrer. Preventing the diversion and abuse of prescription drugs. Footnote 2 Figure 2 compares the growth of key market segments in and as of end of Q2. Further, we are committed to providing health care professionals with balanced information and to support those who provide education on ADHD. Return to footnote 37 referrer. This SWOT analysis is applied at an industry level so the internal factors classified as strengths or weaknesses will be at the industry level while external factors classified as opportunities or threats will be along the broader operating environment for the industry in Canada. Safe disposal of prescription medicine. Return to footnote 24 referrer. The top corporations in Canada in had posted a four-year compound annual growth of 8. Many biopharma SMEs ceased to exist during the recent economic downturn. Biological Response Modifiers are anti- TNF monoclonal antibody biologics for the treatment of diseases associated with autoimmune disorders such as rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, psoriasis, hidradenitis suppurativa and refractory asthma. For brand companies, genericization erodes the margins of branded products. Biologics continue to become increasingly dominant in market share and as an exceptional driver of market growth. Verified Online Pharmacies Verification Program. At the same time, companies will seek market diversification to reduce risk. Return to footnote 60 referrer. Return to footnote 2 referrer Footnote 3 Biotechnology drugs as defined in IMS Pharma reports include products pharmaceutical or vaccine that have been produced in living organisms and manufactured via recombinant DNA technology. For example, new products launched in the Canadian market in accounted for 0. Footnote 39 During these years, the canadian for Canada's biotech industry was enhanced and well regarded. This discussion paper does not examine the Canadian distribution canadian. Ranbaxy, an India-based company is a top generic selling company in Canada came under the control of Japanese pharmaceutical pharma, Daiichi Sankyo in Footnotes Footnote 1 Latest full year annual data available at time of writing Return to footnote 1 referrer Footnote 2 Specialty pharmaceuticals are medicines that treat specific, complex chronic diseases with four or more of the following attr ibutes:

Amongst the top 10 selling generic corporations, four of the corporations have manufac turing facilities in Canada: The top corporations in Canada in had posted a four-year compound annual growth of 8. Return to footnote 61 referrer Footnote 62 Industry Canada research Return to footnote 62 referrer Footnote 63 http: SWOT analyses are usually done across two dimensions—environmental factors that are internal to a firm and external factors to that same firm. Purdue Pharma Canada believes its responsibility goes beyond the provision of innovative medicines. The response to conditions in the global industry since has been an onslaught of mergers and acquisitions as companies sought to consolidate their cost base, expand research pipelines and broaden their geographic market reach. By , biotechnology Footnote 3 and specialty drugs lead growth while the generic segment struggled with negative growth. IMS anticipates the leading products in the global market place will be specialty products and biologics in the area of oncology, autoimmune, antivirals, immunostimulants, immunosuppressants and multiple sclerosis Footnote Footnotes Footnote 1 Latest full year annual data available at time of writing Return to footnote 1 referrer Footnote 2 Specialty pharmaceuticals are medicines that treat specific, complex chronic diseases with four or more of the following attr ibutes: In addition to factors discussed in the previous sections, this section highlights several broader trends that are expected to shape the outlook for pharmaceutical industry and the level of investment in Canada over the next several years. The proceeding sections discuss in greater details the market environment of the four key segments of companies in the Canadian pharmaceutical industry. Return to footnote 54 referrer. Return to footnote 5 2 referrer Footnote 53 Provincial collaboration as part of the Health Care Innovation Working Group , of the Council of Federation—an intergovernmental secretariat comprising of Canadian premiers. Return to footnote 20 referrer. As part of our corporate responsibility program, we have four areas of focus:. The financial impact from this loss of exclusivity to major brand products is a central challenge to the performance of brand companies. The contrast in market growth between developed and emerging markets is triggering critical investment choices for most MNEs. The performance of companies operating in the Canadian market has been challenged by slower growth in sales and waning profitability. Collaboration among HCPs, HCOs and the pharmaceutical industry is essential to improving the quality of life of Canadians as it drives scientific advancements, enhances medical education, and promotes health literacy. The compound annual cznadian of the top pharma corporation, based on their sales, was 3. Return to footnote 47 referrer. Return to footnote 18 referrer, canadian pharma. Figure 4 illustrates this general trend of fewer full benefit listings of new products in the four largest public formularies in Canada. The Biotech canadian segment includes some oncology products.